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GLP-1 Basics
Updated October 2026 · 4 min read · Reviewed against published research
Key Takeaway
GLP-1 receptor agonists mimic a natural gut hormone that helps regulate blood sugar, appetite and digestion.
What is GLP-1?
Glucagon-like peptide-1 is a hormone released by the intestine after eating. It signals the pancreas to release insulin, slows stomach emptying and acts on appetite centers in the brain.
How the medications work
GLP-1 medications activate the same receptors for longer than the natural hormone. Some newer medications also act on a second hormone pathway (GIP).
Who uses them
Specific products are FDA-approved for type 2 diabetes, chronic weight management, or cardiovascular risk reduction. Eligibility is decided with a qualified clinician.
Questions for your healthcare provider
- Is a GLP-1 medication appropriate for my health history?
- Which product and indication applies to me?
- What side effects should I watch for?
- How should I adjust nutrition and exercise?
- What happens if I stop the medication?
Keep learning — free
Join GLP-1 Academy for free guides and The GLP-1 Brief.
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